Examination of the Vinylogous Mannich Reaction with a 1,3-Diketoaldeyde
This project focused on the organic chemistry reaction the vinylogous Mannich reaction. This reaction forms a carbon-carbon bond between an imine (formed from an aldehyde and amine) and a dienolate through the use of a BINOL-based catalyst. We varied the aldehyde component of this 3-component reaction by using a 1,3-diketoaldehyde. We observed that the final product was our expected cyclic tetrahydropyridine.