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ISOLATION AND CHARACTERIZATION OF CHLORAMPHENICOL RESISTANT MITOCHONDRIAL MUTANTS IN SACCHAROMYCES CEREVISIAE. (2014-05-04)Chloramphenicol is a broad spectrum antibiotic, cheaply and easily available. It works by inhibiting protein synthesis in prokaryotes such as E. coli. Its main mode of action is via its binding to the large ribosomal subunit ...