Tissue remodeling has been used as a model to study cancer. It is also an important process during the development of Drosophila melanogaster. During D. melanogaster metamorphosis, which is the transition from the larva ...

Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by progressive neuronal and synaptic degeneration, as well as decreased cognition over time. AD is prevalent in today’s society, comprising ...

Programmed cell death (PCD) serves a variety of key roles during development and homeostasis. In most cases, PCD occurs via apoptosis, a highly orchestrated process that is primarily dependent on the activity of caspase ...

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the aggregation and hyperphosphorylation of the microtubule-associated protein, tau. It is characterized by a variety of cognitive and behavioral ...

Autophagy, the catabolic mechanism whereby stored nutrients are recycled, and the breakdown of problematic proteins and organelles within a cell, is an essential process necessary for maintenance of cellular homeostasis. ...

The larval fat bodies of Drosophila melanogaster are responsible for storing energy from the larval feeding stages for use during pupal development. In most larval tissues, programmed cell death (PCD) is triggered by two ...

Autophagy is the mechanism by which an organism can dispose of parts of its cells. This mechanism plays a vital role in many human diseases such as cancer and neurodegenerative diseases, includings Alzheimer's disease ...

Tauopathies are a class of neurodegenerative diseases characterized by the abnormal phosphorylation and accumulation of the protein, tau. This abnormal accumulation occurs in both neuronal and glial cells and correlates ...

The ketogenic diet is a low carbohydrate, high fat diet that is thought to be beneficial to health. Due to the low intake of carbohydrates in the ketogenic diet, the main energy fuel, glucose is depleted, and insulin levels ...

After Drosophila melanogaster undergoes metamorphosis, the fly breaks free of the pupal case in a process called eclosion. Pharate adult lethality is a phenomenon in which the developed fly fails to eclose and dies inside ...