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Coordination between Insulin Signaling and Ecdysone Signaling during Drosophila melanogaster Development
Insulin signaling is a remarkably conserved pathway that regulates nutrient storage and release in vertebrates and invertebrates. In Drosophila, growth and development are balanced through a mechanism involving insulin and ...
Investigating Octopaminergic/Tyraminergic Signaling and Tau Toxicity in a Drosophila Model of Alzheimer's Disease
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the presence of filamentous tau inclusions. Clinical studies have shown that the locus coeruleus (LC), the main source of noradrenaline in the brain ...
Insulin-like Receptor: The First Step into Drosophila melanogaster's Insulin-signaling Pathway
Many details about the mechanisms that regulate homeostasis still remain unknown, and metabolic diseases continue to cause a great deal of human suffering. In order to further our understanding of the mechanisms underlying ...