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Genetic Analysis of Tissue Remodeling and Lipid Storage in Drosophila melanogaster
Tissue remodeling has been used as a model to study cancer. It is also an important process during the development of Drosophila melanogaster. During D. melanogaster metamorphosis, which is the transition from the larva ...
Genetic Analysis of Programmed Cell Death
The larval fat bodies of Drosophila melanogaster are responsible for storing energy from the larval feeding stages for use during pupal development. In most larval tissues, programmed cell death (PCD) is triggered by two ...
The role of Matrix metalloproteinase-2 in Drosophila melanogaster prepupal and pupal fat body autophagy
Autophagy is the mechanism by which an organism can dispose of parts of its cells. This mechanism plays a vital role in many human diseases such as cancer and neurodegenerative diseases, includings Alzheimer's disease ...
Tau isoform-specific effects on lifespan in a Drosophila melanogaster model of glial tauopathy
Tauopathies are a class of neurodegenerative diseases characterized by the abnormal phosphorylation and accumulation of the protein, tau. This abnormal accumulation occurs in both neuronal and glial cells and correlates ...
The Effects of Ketogenic Supplements on Protein Expression and Autophagy in The Drosophila melanogaster Feeding Third Instar Larval Fat Body
The ketogenic diet is a low carbohydrate, high fat diet that is thought to be beneficial to health. Due to the low intake of carbohydrates in the ketogenic diet, the main energy fuel, glucose is depleted, and insulin levels ...
The role of Aurora-A in Drosophila melanogaster fat body cell migration
After Drosophila melanogaster undergoes metamorphosis, the fly breaks free of the pupal case in a process called eclosion. Pharate adult lethality is a phenomenon in which the developed fly fails to eclose and dies inside ...