The metamorphosis of Drosophila melanogaster results in destruction of many larval tissues by programmed cell death (PCD). PCD is regulated by the steroid hormone 20-hydroxyecdysone (ecdysone) (Yin et al., 2007). PCD is ...

ABSTRACT Understanding the genetic control of development is both important and exciting because it has the potential to lead us to revolutionary discoveries that could provide advancements in numerous fields ...

Insulin signaling is a remarkably conserved pathway that regulates nutrient storage and release in vertebrates and invertebrates. In Drosophila, growth and development are balanced through a mechanism involving insulin and ...

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the presence of filamentous tau inclusions. Clinical studies have shown that the locus coeruleus (LC), the main source of noradrenaline in the brain ...

Many details about the mechanisms that regulate homeostasis still remain unknown, and metabolic diseases continue to cause a great deal of human suffering. In order to further our understanding of the mechanisms underlying ...

Sexual reproduction has fascinated scientists for centuries. The analysis of animal sexual behavior in other animals has helped to enlighten us about human sexual behavior 1. However, it has been argued that our mating ...

Tissue remodeling is an essential process that occurs in multicellular organisms and is essential for the growth, development, and health of any organism. Drosophila melanogaster is an important organism for the study ...

Tissue remodeling is vital to the health of any multicellular organism. Drosophila melanogaster, which undergoes tissue remodeling during metamorphosis, provides an excellent model to study this process due to highly ...

Families of protein kinases have been conserved over millions of years, and they play important roles in many cellular processes such as the cell cycle, differentiation, and signal transduction (Neiman, 1993). Doa, or ...

Tissue remodeling is an important process in multicellular organisms that is necessary for processes such as wound healing and tumor metastasis. For remodeling to occur, connective proteins of the extracellular matrix ...