Browsing Student Theses and Honors Collection by Author "Bacon, Sarah"
Now showing items 1-16 of 16
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Bouncing back: Immune regulated healing in the rat uterus after labor and delivery
Ramsden, Kristina (2019-05-15)The uterus is extensively remodeled by pregnancy. These profound changes must be reversed after labor and delivery. The immune system is dynamic in this progression because of immune cell’s abilities to influence healing ... -
Characterizing Heat Shock Protein Expression Patterns in a Fruit Fly Model of Glial Tauopathy
Saha, Atreyi (2016-05-26)Tauopathies are degenerative diseases characterized by the accumulation of aberrantly phosphorylated tau in both neuronal and glial cells. The aggregation and fibrilization of tau in both neuronal and glial cells is a ... -
DENTAL ARCHAEOLOGY OF THREE POPULATIONS OF CHRISTIANS AND NON-MUSLIMS IN POLLENTIA, MALLORCA
de Paula, Bennett (2017-06-30)The diet, health, nutrition, and genetics of an individual leave unique and identifiable markers on dental remains. Those markers can be used to understand the diet and health of an ancient population. This study presents ... -
Development of a LAMP Assay to Screen for Animal Chlamydiosis
Schlusser, Katherine (2014-07-07)Chlamydial species are gram-negative bacteria that are obligate intracellular parasites. They can infect humans, avians, ruminants, guinea pigs, mice, cats, and pigs. Chlamydiosis produces a wide range of health problems ... -
Differential Expression of an Endogenous Retrovirus in MAIDS Susceptible (C57BL/6) Versus Resistant (BALB/c) Mice
Socha, Amanda (2011-02-16)Murine acquired immunodeficiency syndrome (MAIDS) is a retrovirus-induced disease in mice that results from infection with a specific mixture of Murine Leukemia Virus (MuLV) known as LP-BM5. The two strains of mice used ... -
Macrophage Phenotype Differentiation in the Rat Uterus during Normal and Diabetic Pregnancies
Stampouloglou, Eleni (2011-05-19)Macrophages are the most common type of immune cell in the pregnant uterus. Depending on the tissue microenvironment, macrophages assume one of two broad phenotypes. In general, M1 macrophages destroy extracellular pathogens ... -
Macrophage-Mediated Efferocytosis in Rat Uterine Remodeling
Mishra, Gargi (2018-06-21)Macrophages are professional phagocytes that survey the body for pathogens and secrete biomolecules relevant to many cellular processes. Our lab identified the presence of macrophages around the rat uterine lumen and within ... -
Mouse Liver Development: Analyzing the Relationship Between the Liver and Endothelial Cells Through Whole Mount In Situ Hybridization
Clark, Emily (2018-05-09)The liver’s function as a filtering organ leaves it vulnerable to toxin- related diseases such as cirrhosis, and cancer. Studying liver development in the murine embryo allows for in vivo investigation of the process in a ... -
Nothing happens until something moves: Exploring the Kinetic Energy of Body, Sound and Space through Movement
Wiss, Margaret (2016-06-30)Nothing happens until something moves? If nothing is happening where is the movement initiated from? Life moves in a series of reactions and changes in energy. Movement is produced from the conversion of potential ... -
Open Complex Contacts: An Analysis of the T5 N25 Discriminator Region Interaction with E. coli RNA Polymerase
White, Cassandra (2011-02-16)E. coli RNA polymerase (RNAP) is known to contact a promoter via the UP element and its -35 and -10 hexameric sequences during the first stage of transcription to transition into a catalytically competent open complex. ... -
Placental Gene Expression and Maternal Allergic Asthma: Investigating Neurodevelopmental Pathways in a Mouse Model of Autism Spectrum Disorders
Emerson, Felicity (2017-06-27)Recent epidemiological studies have suggested that mothers with onset allergies or asthma during pregnancy are at an increased risk for having a child with autism spectrum disorders (ASD). A novel mouse model of maternal ... -
Primary Culture of Drosophila melanogaster Glial Cells
Hussain, Uzma (2014-05-06)Glial cells are one of the most abundant cell types in human brains, yet there is very little that we actually know about these cells. We do know that glial cells are important and vital regulators of the function of the ... -
The Right to a Protected Pregnancy: Models of Perinatal Support for Women in Massachusetts Correctional Facilities
Bommer, Cassidy (2013-07-01)Today, over 1.2 million women in the United States are incarcerated, on parole, or on probation. In Massachusetts alone, 2,000 women are currently incarcerated, 8,000 annually. Each year, more than 200 of them are pregnant. ... -
The role of calcium in amoeboid movement: Results with fluorescent indicator dyes
Soden, Marta (2011-02-16)The cytoskeleton of the unicellular organism Amoeba proteus includes a cortical network of filamentous actin directly beneath and attached to the plasma membrane. The contraction of this layer, occurring primarily in the ... -
Transforming Growth Factor-β in Breast Milk from Women with Breast Biopsies
Mahmood, Sidra (2012-05-21)About 1 in 8 (12%) American women will develop invasive breast cancer during their lifetime, and around 40,000 of them are estimated to die from it in 2012 alone (American Cancer Society, 2012). Diagnosis of breast cancer ... -
Zebrafish Cardiac Development: The Effects of Retinoic Acid on Heart Tube Morphology and Function
Markowitz, Molly (2012-05-17)The formation of a heart occurs through a series of dynamic developmental events where individual cells differentiate, migrate, fuse, and loop to form a muscular tube which then has the ability to pump blood throughout the ...